Slay the Spire 2‘s early access build has over 250 relics to find on a run, and all of them have unique in-game effects.
Some relics are limited to use with specific characters. However, many of them can be used with all characters. Let’s quickly look at all the relics and their in-game effects, so you have a clear idea about which ones to draft on priority.
All relics and effects in Slay the Spire 2
The tables below have all the relics that you can find in the current build. I have separated the tables as per their rarities.
Common
| Relics | How it works |
|---|---|
| Amethyst Aubergine | Enemies drop 10 additional Gold |
| Anchor | Start each combat with 10 Block |
| Bag of Preparation | At the start of each combat, draw 2 additional cards |
| Blood Vial | At the start of each combat, heal 2 HP |
| Bone Flute | Whenever Osty attacks, gain 2 Block. |
| Book of Five Rings | Every 5 cards you add to your Deck, heal 15 HP. |
| Bronze Scales | Start each combat with 3 Thorns. |
| Centennial Puzzle | The first time you lose HP each combat, draw 3 cards. |
| Data Disk | Start each combat with 1 Focus. |
| Fencing Manual | At the start of each combat, Forge 10. |
| Festive Popper | At the start of each combat, deal 9 damage to ALL enemies. |
| Gorget | At the start of each combat, gain 4 Plating. |
| Happy Flower | Every 3 turns, gain Colorless Energy. |
| Juzu Bracelet | Regular enemy combats are no longer encountered in ? rooms. |
| Lantern | Start each combat with an additional Colorless Energy. |
| Meal Ticket | Whenever you enter a shop room, heal 15 HP. |
| Oddly Smooth Stone | Start each combat with 1 Dexterity. |
| Pendulum | Whenever you shuffle your Draw Pile, draw a card. |
| Permafrost | The first time you play a Power each combat, gain 6 Block. |
| Potion Belt | Upon pickup, gain 2 potion slots. |
| Red Skull | While your HP is at or below 50%, you have 3 additional Strength. |
| Regal Pillow | Whenever you Rest, heal an additional 15 HP. |
| Snecko Skull | Whenever you apply Poison, apply an additional 1 Poison. |
| Strawberry | Upon pickup, raise your Max HP by 7. |
| Strike Dummy | Cards containing “Strike” deal 3 additional damage. |
| Tiny Mailbox | Whenever you Rest, procure a random potion. |
| Vajra | Start each combat with 1 Strength. |
| Venerable Tea Set | Whenever you enter a Rest Site, start the next combat with an additional 2 Colorless Energy. |
| War Paint | Upon pickup, Upgrade 2 random Skills. |
| Whetstone | Upon pickup, Upgrade 2 random Attacks. |
Uncommon
| Relics | How it works |
|---|---|
| Akebeko | At the start of each combat, gain 8 Vigor. |
| Bag of Marbles | At the start of each combat, apply 1 Vulnerable to ALL enemies. |
| Bellows | The first Hand you draw each combat is Upgraded. |
| Book Repair Knife | Whenever a non-Minion enemy dies to Doom, heal 3 HP. |
| Bowler Hat | Gain 20% additional Gold. |
| Candelabra | At the start of your 2nd turn, gain 2 Colorless Energy. |
| Eternal Feather | For every 5 cards in your Deck, heal 3 HP whenever you enter a Rest Site. |
| Funerary Mask | At the start of each combat, add 3 Souls into your Draw Pile. |
| Galactic Dust | For every Star spent, gain 10 Block. |
| Gold-Plated Candles | Your rightmost Orb triggers its passive an additional time. |
| Gremlin Horn | Whenever an enemy dies, gain Colorless Energy and draw 1 card. |
| Horn Cleat | At the start of your 2nd turn, gain 14 Block. |
| Joss Paper | Every 5 times you Exhaust a card, draw 1 card. |
| Kusarigama | Every time you play 3 Attacks in a single turn, deal 6 damage to a random enemy. |
| Letter Opener | Every time you play 3 Skills in a single turn, deal 5 damage to ALL enemies. |
| Lucky Fysh | Whenever you add a card to your Deck, gain 15 Gold. |
| Mercury Hourglass | At the start of your turn, deal 3 damage to ALL enemies. |
| Miniature Cannon | Upgraded Attacks deal 3 additional damage. |
| Nunchaku | Every time you play 10 Attacks, gain Colorless Energy. |
| Orichalcum | If you end your turn without Block, gain 6 Block. |
| Ornamental Fan | Every time you play 3 Attacks in a single turn, gain 4 Block. |
| Pantograph | At the start of each Boss combat, heal 25 HP. |
| Paper Phrog | Enemies with Vulnerable take 75% more damage rather than 50%. |
| Parrying Shield | If you end a turn with at least 10 Block, deal 6 damage to a random enemy. |
| Pear | Upon pickup, raise your Max HP by 10. |
| Pen Nib | Every 10th Attack you play deals double damage. |
| Petrified Toad | At the start of each combat, procure a Potion-Shaped Rock. |
| Planisphere | Whenever you enter a ? room, heal 4 HP. |
| Red Mask | At the start of each combat, apply 1 Weak to ALL enemies. |
| Regalite | Whenever you create a Colorless card, gain 2 Block. |
| Reptile Trinket | Whenever you use a potion, gain 3 Strength this turn. |
| Ripple Basin | If you did not play any Attacks during your turn, gain 4 Block. |
| Self-Forming Clay | Whenever you lose HP in combat, gain 3 Block next turn. |
| Sparkling Rouge | At the start of your 3rd turn, gain 1 Strength and 1 Dexterity. |
| Stone Cracker | At the start of Boss combats, Upgrade 3 random cards in your Draw Pile for the rest of combat. |
| Symbiotic Virus | At the start of each combat, Channel 1 Dark. |
| Tingsha | Whenever you discard a card during your turn, deal damage to a random enemy for each card discarded. |
| Tuning Fork | Every time you play 10 Skills, gain 7 Block. |
| Twisted Funnel | At the start of each combat, apply 4 Poison to ALL enemies. |
| Vambrance | The first time you gain Block from a card each combat, double the amount gained. |
Rare
| Relic | How it works |
|---|---|
| Art of War | If you do not play any Attacks during your turn, gain an additional Colorless Energy next turn. |
| Beating Remnant | You cannot lose more than 20 HP in a single turn. |
| Big Hat | At the start of each combat, add 2 random Ethereal cards into your Hand. |
| Bookmark | At the end of each turn, lower the cost of a random Retained card by 1 until played. |
| Captain’s Wheel | At the start of your 3rd turn, gain 18 Block. |
| Chandelier | At the start of your 3rd turn, gain 3 Colorless Energy. |
| Charon’s Ashes | Whenever you Exhaust a card, deal damage to ALL enemies. |
| Cloak Clasp | At the end of your turn, gain 1 Block for each card in your Hand. |
| Demon Tongue | The first time you lose HP on your turn, heal HP equal to the amount lost. |
| Emotion Chip | If you lost HP during the previous turn, trigger the passive ability of all Orbs at the start of your turn. |
| Frozen Egg | Whenever you add a Power into your Deck, Upgrade it. |
| Gambling Chip | At the start of each combat, discard any number of cards, then draw that many. |
| Game Piece | Whenever you play a Power, draw 1 card. |
| Girya | You can now gain Strength at Rest Sites. |
| Helical Dart | Whenever you play a Shiv, gain 1 Dexterity this turn. |
| Ice Cream | Energy is now conserved between turns. |
| Intimidating Helmet | Whenever you play a card that costs 1 Colorless Energy or more, gain 4 Block. |
| Ivory Tile | Whenever you play a card that costs 3 Colorless Energy or more, gain 1 Colorless Energy. |
| Kunai | Every time you play 3 Attacks in a single turn, gain 1 Dexterity. |
| Lasting Candy | Every other combat, your card rewards gain an additional Power. |
| Lizard Tail | When you would die, heal to 50% of your Max HP instead. |
| Lunar Pastry | At the end of your turn, gain Star. |
| Mango | Upon pickup, raise your Max HP by 14. |
| Meat on the Bone | If your HP is at or below 50% at the end of combat, heal 12 HP. |
| Metronome | The first time you Channel 7 Orbs each combat, deal damage to ALL enemies. |
| Mini Regent | The first time you spend Star each turn, gain 1 Strength. |
| Molten Egg | Whenever you add an Attack card to your Deck, Upgrade it. |
| Mummified Hand | Whenever you play a Power, a random card in your Hand is free to play that turn. |
| Old Coin | Upon pickup, gain 300 Gold. |
| Orange Dough | At the start of each combat, add 2 random Colorless cards into your Hand. |
| Paper Krane | Enemies with Weak deal 40% less damage to you rather than 25%. |
| Pocketwatch | Whenever you play 3 or fewer cards during your turn, draw 3 additional cards at the start of your next turn. |
| Power Cell | At the start of each combat, add 2 zero-cost cards from your Draw Pile into your Hand. |
| Prayer Wheel | Normal enemies drop an additional card reward. |
| Rainbow Ring | The first time you play an Attack, Skill, and Power each turn, gain 1 Strength and 1 Dexterity. |
| Razor Tooth | Every time you play an Attack or Skill, Upgrade it for the remainder of combat. |
| Ruined Helmet | The first time you gain Strength each combat, double the amount gained. |
| Shovel | You can now dig at Rest Sites to obtain a random Relic. |
| Shuriken | Every time you play 3 Attacks in a single turn, gain 1 Strength. |
| Stone Calendar | At the end of turn 7, deal 52 damage to ALL enemies. |
| Sturdy Clamp | Up to 10 Block persists across turns. |
| The Courier | The merchant no longer runs out of cards, relics, or potions, and his prices are reduced by 20%. |
| Tough Bandages | Whenever you discard a card during your turn, gain 3 Block. |
| Toxic Egg | Whenever you add a Skill into your Deck, Upgrade it. |
| Tungsten Rod | Whenever you would lose HP, lose 1 less. |
| Unceasing Top | Whenever you have no cards in Hand during your turn, draw a card. |
| Unsettling Lamp | Each combat, the first time you play a card that Debuffs an enemy, double its effect. |
| Vexing Puzzlebox | At the start of each combat, add a random card into your Hand. It costs 0 Colorless Energy. |
| White Beast Stature | Potions always appear in combat rewards. |
| White Star | Elites drop an additional Rare card reward. |
Shop
| Relic | How it works |
|---|---|
| Belt Buckle | While you have no potions, you have 2 additional Dexterity. |
| Bread | At the start of your first turn, lose 2 Colorless Energy. At the start of all other turns, gain Colorless Energy. |
| Brimstone | At the start of your turn, gain 2 Strength and ALL enemies gain 1 Strength. |
| Burning Sticks | The first time each combat you Exhaust a Skill, add a copy of it to your Hand. |
| Cauldron | Upon pickup, brews 5 random potions. |
| Chemical X | The effects of your cost X cards are increased by 2. |
| Dingy Rug | Card rewards can now contain Colorless cards. |
| Dolly’s Mirror | Upon pickup, obtain an additional copy of a card in your Deck. |
| Dragon Fruit | Whenever you gain Gold, raise your Max HP by 1. |
| Ghost Seed | Strikes and Defends gain Ethereal. |
| Gnarled Hammer | Upon pickup, Enchant up to 3 Attacks with Sharp 3. |
| Kifuda | Upon pickup, Enchant up to 3 cards with Adroit. |
| Lava Lamp | At the end of combat, Upgrade all card rewards if you took no damage. |
| Lee’s Waffle | Upon pickup, raise your Max HP by 7 and heal all of your HP. |
| Membership Card | 50% discount on all products! |
| Miniature Tent | You may choose any number of options at Rest Sites. |
| Mystic Lighter | Enchanted Attacks deal 9 additional damage. |
| Ninja Scroll | At the start of each combat, add 3 Shivs into your Hand. |
| Orrery | Upon pickup, gain 5 card rewards. |
| Punch Dagger | Upon pickup, Enchant an Attack with Momentum 5. |
| Ringing Triangle | Retain your Hand on the first turn of combat. |
| Royal Stamp | Upon pickup, choose an Attack or Skill in your Deck to Enchant with Royally Approved. |
| Runic Capacitor | If you end your turn with no cards in your Hand, deal 20 damage to ALL enemies. |
| Screaming Flagon | If you end your turn with no cards in your Hand, deal 20 damage to ALL enemies. |
| Sling of Courage | Start each Elite combat with 2 Strength. |
| The Abacus | Whenever you shuffle your Draw Pile, gain 6 Block. |
| Toolbox | At the start of each combat, choose 1 of 3 random Colorless cards and add the chosen card into your Hand. |
| Undying Sigil | Enemies with at least as much Doom as HP deal 50% less damage. |
| Vitruvian Minion | Cards containing “Minion” deal double damage and gain double Block. |
| Wing Charm | A random card in each card reward is Enchanted with Swift 1. |
Ancient
| Relic | How it works |
|---|---|
| Alchemical Coffer | Upon pickup, gain 4 potion slots filled with random potions. |
| Arcane Scroll | Upon pickup, obtain a random Rare Card to add to your Deck. |
| Archaic Tooth | Upon pickup, Transform a starter card with an ancient version. |
| Astrolabe | Upon pickup, Transform 3 cards, then Upgrade them. |
| Beautiful Bracelet | Upon pickup, choose 3 cards in your Deck. Enchant them with Swift 3. |
| Biiig Hug | Upon pickup, remove 4 cards from your Deck. Whenever you shuffle your Draw Pile, add a Soot into your Draw Pile. |
| Black Star | Elites drop an additional Relic when defeated. |
| Blessed Antler | Gain Colorless Energy at the start of each turn. At the start of each combat, shuffle 3 Dazed into your Draw Pile. |
| Blood-Soaked Rose | Upon pickup, add 1 Enthralled to your Deck. Gain Colorless Energy at the start of each turn. |
| Booming Conch | At the start of Elite combats, draw 2 additional cards. |
| Brilliant Scarf | The 5th card you play each turn is free. |
| Calling Bell | Upon pickup, obtain a unique Curse and 3 Relics. |
| Choices Paradox | At the start of each combat, add 1 of 5 random cards into your Hand. Add Retain to the chosen card. |
| Claws | Upon pickup, Transform up to 6 cards into Maul. |
| Crossbow | At the start of your turn, add a random Attack into your Hand. It costs 0Colorless Energy this turn. |
| Cursed Pearl | Upon pickup, receive Greed. Gain 333 Gold. |
| Delicate Frond | At the start of each combat, fill all empty potion slots with random potions. |
| Diamond Diadem | Whenever you play 2 or fewer cards in a turn, take half damage from enemies. |
| Distinguished Cape | Upon pickup, lose 9 Max HP. Add 3 Apparitions to your Deck. |
| Driftwood | You may reroll each card reward once. |
| Dusty Tome | Upon pickup, obtain an Ancient Card. |
| Ectoplasm | You can no longer gain Gold. Gain Colorless Energy at the start of each turn. |
| Electric Shrymp | Upon pickup, Enchant a Skill with Imbued. |
| Empty Cage | Upon pickup, remove 2 cards from your Deck. |
| Fiddle | At the start of each turn, draw 2 additional cards. You may not draw cards during your turn. |
| Fur Coat | Upon pickup, mark 7 random combats. Enemies in those rooms have 1 HP. |
| Glass Eye | Upon pickup, obtain 2 Common cards, 2 Uncommon cards, and 1 Rare card. |
| Glitter | Enchant all card rewards with Glam. |
| Golden Compass | Upon pickup, replace the Act 2 Map with a single special path. |
| Golden Pearl | Upon pickup, gain 150 Gold. |
| Iron Club | Every 4 cards you play, draw 1 card. |
| Jeweled Mask | At the start of combat put a random Power from your Draw Pile into your Hand, it’s free to play. |
| Jewelry Box | Upon pickup, add 1 Apotheosis to your Deck. |
| Large Capsule | Upon pickup, obtain 2 random Relics. Add an additional Strike and Defend to your Deck. |
| Lava Rock | The Act 1 Boss drops 2 Relics. |
| Lead Paperweight | Upon pickup, choose 1 of 2 Colorless cards to add to your Deck. |
| Leafy Poultice | Upon pickup, Transform 1 of your Strikes and 1 of your Defends and lose 10 Max HP. |
| Looming Fruit | Upon pickup, raise your Max HP by 31. |
| Lord’s Parasol | When you encounter the Merchant, immediately obtain EVERYTHING he sells. |
| Lost Coffer | Upon pickup, gain 1 card reward and procure 1 random potion. |
| Massive Scroll | Upon pickup, choose 1 of 3 Multiplayer Colorless Cards to add to your Deck. |
| Meat Cleaver | You may Cook at Rest Sites. |
| Music Box | Create an Ethereal copy of the first Attack you play each turn. |
| Neow’s Torment | Upon pickup, add 1 Neow’s Fury to your Deck. |
| New Leaf | Upon pickup, Transform 1 card. |
| Nutritious Oyster | Upon pickup, raise your Max HP by 11. |
| Nutritious Soup | Upon pickup, Enchant all Strikes in your Deck with Tezcatara’s Ember. |
| Pael’s Blood | At the start of your turn, draw 1 additional card. |
| Pael’s Claw | Upon pickup, Enchant all Defends with Goopy. |
| Pael’s Eye | The first time each combat you end your turn without playing cards, Exhaust your Hand, and take an extra turn. |
| Pael’s Flesh | Gain an additional Colorless Energy at the start of your 3rd turn, and every turn after that. |
| Pael’s Growth | Upon pickup, Enchant a card with Clone. |
| Pael’s Horn | Upon pickup, add 2 Relax to your Deck. |
| Pael’s Legion | Doubles Block gained from a card, then goes to sleep for 2 turns. |
| Pael’s Tears | If you end your turn with unspent Colorless Energy, gain an additional Colorless Energy next turn. |
| Pael’s Tooth | Upon pickup, remove 5 cards from your Deck. After each combat, randomly add 1 back Upgraded. |
| Pael’s Wing | You may sacrifice card rewards to Pael. Every 2 sacrifices, obtain a Relic. |
| Pandora’s Box | Transform ALL Strikes and Defends. |
| Philosopher’s Stone | Gain Colorless Energy at the start of each turn. ALL enemies start combat with 1 Strength. |
| Pomander | Upon pickup, Upgrade a card. |
| Precarious Shears | Upon pickup, remove 2 cards from your Deck and take 13 damage. |
| Precise Scissors | Upon pickup, remove 1 card from your Deck. |
| Preserved Fog | Upon pickup, remove 5 cards from your Deck. Add Folly to your Deck. |
| Prismatic Gem | Gain Colorless Energy at the start of each turn. Card rewards now contain cards from other colors. |
| Pumpkin Candle | Gain Colorless Energy at the start of each turn. Extinguishes at the start of Act 3. |
| Radiant Pearl | At the start of each combat, add 1 Luminesce into your Hand. |
| Runic Pyramid | At the end of your turn, you no longer discard your Hand. |
| Sai | At the start of your turn, gain 7 Block. |
| Sand Castle | Upon pickup, Upgrade 6 random cards. |
| Scroll Boxes | Upon pickup, lose all Gold and choose 1 of 2 packs of cards to add to your Deck. |
| Sea Glass | See 15 cards from another character. Choose any number of them to add to your Deck. |
| Seal of Gold | At the start of your turn, spend 5 Gold to gain Colorless Energy. |
| Sere Talon | Upon pickup, add 2 random Curses and 3 Wishes to your Deck. |
| Signet Ring | Upon pickup, gain 999 Gold. |
| Silver Crucible | The first 3 card rewards you see are Upgraded. The first Treasure Chest you open is empty. |
| Small Capsule | Upon pickup, obtain a random Relic. |
| Snecko Eye | At the start of your turn, draw 2 additional cards. Start each combat Confused. |
| Sozu | Gain Colorless Energy at the start of each turn. You can no longer obtain potions. |
| Spiked Gauntlets | Gain Colorless Energy at the start of each turn. Powers cost 1 more Colorless Energy. |
| Stone Humidifier | Whenever you Rest at a Rest Site, raise your Max HP by 5. |
| Storybook | Upon pickup, add 1 Brightest Flame to your Deck. |
| Tanx’s Whistle | Upon pickup, add 1 Whistle to your Deck. |
| Throwing Axe | The first card you play each combat is played an extra time. |
| Toasty Mittens | At the start of your turn, Exhaust the top card of your Draw Pile and gain 1 Strength. |
| Touch of Orobas | Upon pickup, replace your starter Relic with an Ancient version. |
| Toy Box | Upon pickup, obtain 4 Wax Relics. Every 3 combats, your left-most Wax Relic will melt away. |
| Tri-Boomerang | Choose 3 Attacks in your Deck. Enchant them with Instinct. |
| Velvet Choker | Gain Colorless Energy at the start of each turn. You cannot play more than 6 cards per turn. |
| Very Hot Cocoa | Start each combat with an additional 4 Colorless Energy. |
| War Hammer | Whenever you kill an Elite, Upgrade 4 random cards. |
| Whispering Earring | Gain Colorless Energy at the start of each turn. Vakuu plays your first turn for you. |
| Yummy Cookie | Upon pickup, Upgrade 4 cards. |
Event
| Relic | How it works |
|---|---|
| Big Mushroom | Upon pickup, raise your Max HP by 20. At the start of each combat, draw 2 fewer cards. |
| Bing Bong | Whenever you add a card to your Deck, add one additional copy. |
| Bone Tea | At the start of the next combat, Upgrade your starting hand. |
| Brydpip | Upon pickup, gain the card Byrd Swoop. A Byrdpip will accompany you in battles. |
| The Chosen Cheese | At the end of combat, gain 1 Max HP. |
| Darkstone Periapt | Whenever you obtain a Curse, raise your Max HP by 6. |
| Daughter of the Wind | Whenever you play an Attack, gain 1 Block. |
| Dream Catcher | Whenever you Rest, you may add a card to your Deck. |
| Ember Tea | At the start of the next 5 combats, gain 2 Strength. |
| Anchor | Start each combat with 4 Block. |
| Blood Vial | At the start of each combat, heal 1 HP. |
| Happy Flower | Every 5 turns, gain Colorless Energy. |
| Lee’s Waffle | Upon pickup, heal 10% of your HP. |
| Mango | Upon pickup, raise your Max HP by 3. |
| The Merchant’s Rug | Poor imitation. Does nothing. |
| Orichalcum | If you end your turn without Block, gain 3 Block. |
| Snecko Eye | Start each combat Confused. |
| Strike Dummy | Cards containing “Strike” deal 1 additional damage. |
| Venerable Tea Set | Whenever you enter a Rest Site, start the next combat with an additional Colorless Energy. |
| Forgotten Soul | Whenever you Exhaust a card, deal 1 damage to a random enemy. |
| Fragrant Mushroom | Upon pickup, lose 15 HP and Upgrade 3 random cards. |
| Fresnel Lens | Whenever you add a card that gains Block to your Deck, Enchant it with Nimble 2. |
| Hand Drill | Whenever you break an enemy’s Block, apply 2 Vulnerable. |
| History Course | At the start of your turn, play a copy of your last played Attack or Skill. |
| Lost Wisp | Whenever you play a Power, deal 8 damage to ALL enemies. |
| Maw Bank | Whenever you climb a floor, gain 12 Gold. No longer works when you spend any Gold at the shop. |
| Mr. Struggles | At the start of your turn, deal damage equal to the turn number to ALL enemies. |
| Pollinous Core | Every 4 turns, draw 2 additional cards. |
| Royal Poison | At the start of each combat, lose 4 HP. |
| Swprd of Jade | Start each combat with 3 Strength. |
| Sword of Stone | Transforms into a powerful Relic after defeating 5 Elites. |
| Tea of Discourtesy | At the start of the next combat, shuffle 2 Dazed into your Draw Pile. |
| The Boot | Whenever you would deal 4 or less unblocked attack damage, increase it to 5. |
| Wongo Customer Appreciation Badge | Does nothing. |
| Wongo’s Mystery Ticket | Receive 3 random Relics after 5 combats. |