It would appear that Telltale Games is preparing a brand new adventure for Sam & Max with a third season of mindbending puzzles and faintly embarrassing witticisms. It's called Sam & Max: The Devil's Playhouse.
At least, that's according to the OFLC. The rating board outed the game recently, shedding a little titular light on the future of the Freelance Police. That's all there is at the moment, but considering the last season ended with Episode 5: What's Cooking Beelzebub?, it would appear that we're picking up where we left off. The OFLC says that Episode 1 of The Devil's Playhouse will be called The Penal Zone.
So there you go. More Sam & Max for anybody who's interested. Hooray!