We're yet to see any actual shred of a game, but Killer is Dead has some new artwork that ought to give a bit of a clue as to the game's aesthetic. It's very Japanese, and it's very futuristic. Think, odd-shaped buildings next to blossom trees, and you get the idea.
I'm always excited for any Grasshopper game, because Grasshopper makes games I like to play. It's a good system I have. Really looking forward to seeing where this mysterious project goes.