Dishonored has one hell of a voice cast but Lost's Josh Holloway is not on the bill. Due to some confusion over this on other news sites, Dishonored co-director Harvey Smith cleared this up for us (as well as BethBlog's Twitter).
This rumor likely spawned due to some Wikipedia trolling and Corvo looking an awful lot like Holloway in the game's teaser trailer. The funny thing about this is the character that Holloway was assumed to play is a silent protagonist so go figure that one out.
"Corvo is entirely silent," Smith said. "We let you project onto him, for better or worse."
If you were intending to pick-up Dishonored for Holloway's gruff voice and blazing hot six-pack abs, you'll be sorely disappointed. Good thing the game has a lot more going for it!