After a long, long wait (of only a few months) Duke Nukem Forever is coming to Mac, courtesy of Aspyr Games.
It'll be out this August, and it sounds like a direct port of the long-awaited shooter. If you don't know what Duke Nukem Forever is, I question why you're reading Destructoid at all. But for more details, be sure to check out the review; I largely suspect much of that will apply to Aspyr's port.
Aspyr's own GameAgent.com is offering a 10% discount to all folks who pre-order the game, in addition to free shipping. Mac owners can actually play Duke Nukem Forever on their systems right now using OnLive, if you simply can't wait.
Duke Nukem Forever Coming to the Mac [The Game Agent Blog]