Consider your weekend plans settled
If, like me, you've yet to play the game and are made to feel like a terrible human being as a result, this is likely your best bet as far as running it easily on modern hardware. $9.99 is an easy price to swallow, and while you are at it, take a look at this forum post running through some of the recommended mods. The original soundtrack is also included with the purchase.
If there's a list floating around out there of classic PC titles that need to appear on GOG.com, surely System Shock 2 would have been on it.