In relation to the picture above; I listen to a lot of Podtoid while playing Viva Pinata.
Music in games can be very good. It can also be completely irrelevant to what's actually going on. The radio in GTA IV is excellent, but it's often completely inappropriate to the situation. Is Niko really going to be listening to a talk radio station as he's busting someone out of jail? (I'm not actually complaining about the radio, I know that it can be turned off). Has anyone found your own music to help you pass a particularly difficult level? Beastie Boys 'Sabotage' in combination with Gears of War is absolutely epic. What do you do most of the time with music in games? Do you leave it as is, mute it or replace it with your own?