As we all know, many songs today use samples from video games, so this is the first in a series of howevermany.
Here we have "Ryders" by Saigon & Memphis Bleek.
OK so the above video sampled from Bon Jovi's Runaway as pointed out by Shipero and Murder 64 but don't both tunes remind you of a videogame?
If you don't recognise the sample from the following bonus song, then you need help.
"Super Brooklyn", by Smif N Wessun aka the Cocoa Brothers.