I bought a Wii a few months back, a mostly spontaneous decision that followed actually stumbling upon one of these hard to find little beauties, and because I had a few hundred dollars burning a hole in my pocket.
Since I bought it, I've picked up a half dozen or so games (Zelda, Trauma Centre, Raging Rabbids, WarioWare, RE4, a few others), and have been mostly impressed with the balance of goofy, party-style games, and more immersive, single-player games.
What hasn't impressed me as much is how difficult the Wii is to use in conjunction with two of my other common gaming pass-times -- smoking and drinking.
It's not so bad if you're playing something like WarioWare with a few friends, and handing the Wii-remote around the room, freeing up your hands every once and awhile, and it's not so bad playing something like Wii Sports, which only requires the use of the remote, and leaves one hand free for whatever else you need to be doing -- like smoking or drinking.
But if you're playing something like RE4 or Zelda, which requires both the nunchuck and the Wii-remote, it's sort of a pain in the ass to pick up a beer or smoke a cigarette. About the only thing you can do, outside of taking occasional smoking / drinking breaks from the game, is drape the nunchuck over your lap while you fumble around with your free hand for your booze or cigarettes.
Obviously, with traditional controllers, which require two hands but are a single object, it's quite easy to pull one hand away to grab a drink or a smoke, while your other hand hangs onto the controller until you're ready to play again, but the split controllers on the Wii are certainly a bit less intuitive for those of us looking to booze it up or pollute or lungs while we game.
System-breaking? Hardly. It's a minor annoyance at best, and perhaps I could even use it as an excuse to finally quit smoking (although, really, how geeky an excuse would that be). Until then, I suspect it'll be fumbling and leg-draping.
On a slightly different topic, does anyone else leave their Wii remotes dangling from their wrist when they head to the fridge to grab a cold one? I sure do.