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The Binding of Isaac -- Instruction Manual

The Binding of Isaac is brutally difficult, complicated and incredibly deep. These things combined can also make it a somewhat confusing, clumsy experience for those just starting out. After sinking 100+ hours into this beast, I figured I should at least share some general knowledge that I�ve picked up over that time. Hopefully this will help clear up some questions a few of you have about this mean motherfucker of a game.

This "manual" covers the original game content along with stuff that was added with The Wrath of the Lamb expansion. Although the expansion does make the game significantly more difficult in some ways but also adds a bunch of neat stuff that makes the overall game more fun too. If you don't have it, get it! Also, if you don't have it, a lot of the stuff mentioned below is gonna sound foreign.

Disclaimer: I didn�t fully realize how huge this game was until I started cataloging all the different categories of items and rooms. This was initially supposed to be a �quick reference� guide for newbies to the game but it ended up being much bigger than I planned. The danger of SPOILERS is a possibility, I guess. I don�t go into any depth about the story, specific enemy types or boss strategies. This will most definitely fall into TL;DR territory for most of you but I�m okay with that.



Hoooooooooly shit that took a long time. Of course it�s only after writing this monstrosity that I realize you could have easily just looked at the Wiki or something else online, albeit without my literary touch. Regardless, it�s been done and it was fun to write. I hope this helps to clear up some questions a few of you may have. I may do a combat strategy and basic enemy guide if you guys feel it's necessary. Of course if any veterans out there have any tips or suggestions that I failed to include, please let me know in the comments. That goes for mistakes too!
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About Phoustone of us since 2:05 AM on 02.11.2010

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My name is Eric. I'm 39.
Here are some random things I'm into:

The Buy it/Avoid it Report - back issues
#001 - Ilomilo, Uncharted 2, Infinity Blade, Pac-Man CE DX, Battlefield BC2: Vietnam, PixelJunk Shooter
#002 - Batman: Brave & Bold, DJ Hero 2, Dead Space 2, Bionic Commando Rearmed, Marvel vs. Capcom 3, Bulletstorm
#003 - Pokemon Black/White, PixelJunk Shooter 2, Monster Tale, God of War III, BIT.TRIP RUNNER, Torchlight
#004 - Portal 2, Steel Diver, Sin & Punishment Star Successor, Pilotwings Resort, Crysis 2, Blocks That Matter
#005 - L.A. Noire, Alice Madness Returns, Resident Evil Mercenaries 3D, Shadows of the Damned
#006 - GoldenEye 007, Insanely Twisted Shadow Planet, AC: Brotherhood, Sword & Sworcery EP, Trenched
#007 - Deus Ex: Human Revolution, Jetpack Joyride, Gears of War 3, The Binding of Isaac, Renegade Ops
#008 - Dark Souls, League of Evil, Uncharted 3, Batman: Arkham City, Super Mario 3D Land
#009 - The Buy it/Avoid it Report's Awards - 2011
#010 - Spelunky, Max Payne 3, Trials Evolution, Mario Kart 7, Escape Goat
#011 - Super Hexagon, Tekken Tag Tournament 2, Lollipop Chainsaw, Mark of the Ninja

The Play it/Avoid it Report - back issues
#001 - Bioshock Infinite, Darksiders II, Dead Space 3, Far Cry 3, Sleeping Dogs, Tomb Raider
#002 - Dishonored, DKC: Tropical Freeze, Grand Theft Auto V, Legend of Zelda: Wind Waker HD, Rogue Legacy
#003 - The Binding of Isaac: Rebirth, Mario Kart 8, Middle-earth: Shadow of Mordor, Sunset Overdrive

Secret Moon Base - episodes
Subscribe on iTunes - a podcast about video games and other stuff with my pals knutaf and Occam

Spelunky HD - blogs
Mega Guide - part one
Mega Guide - part two

The Binding of Isaac - blogs
Blood, Shit and Tears - a love letter
Instruction Manual - w/ tips and tricks for beginners
Unlocking Godhead - tips for playing as The Lost

Social Network(s) - ugh
Twitter - @corduroyturtle
Xbox LIVE:Corduroy Turtle
PSN ID:Corduroy_Turtle
Steam ID:17wizards
3DS Code:4639-8962-6190


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