GamersGate has got a glut of offers on this weekend, reducing the Jagged Alliance games and the Men of War franchises by up to 75%. Also on GamersGate, Metro 2033 is cut down by 66% off its usual price. Over on GreenManGaming, there's up to 75% off the price of Telltale's many franchises including The Walking Dead, Puzzle Agent, and errr..... Law & Order.
EA have got The Sims 3 reduced from £39.99 to just £9.99 over on Origin. On Steam, Counterstrike: GO is free to play this weekend and half price if you want to buy the game. The other weekend deal is Borderlands 2 which is 66% off. The Be Mine 8 charity bundle has got a great selection of games for either a single dollar or $5 if you want five extra games thrown in, like Blood Bowl and Slam Bolt Scrappers.
Jordan already let you know about Amazon.com's crazy sales and Andy's already let you know about GOG.com's special Ubisoft promo and competition, so that just leaves me to remind you to put any weekend deals you find in the comments.