After completing multiple Pokemon titles, Twitch Plays Pokemon is still...well... playing. Currently they're working their way through Platinum, with a new twist involved. Players can bet on Pokemon Stadium 2 matches.
While each game isn't nearly as popular as the one before it, it's crazy that there's still an audience, and people willing to play. The first time around was a mild phenomenon for a short while, and I'm kind of glad that it's died down a bit.
Twitch Plays Pokemon [Twitch]