Men's Room Mayhem is basically Flight Control, with blood, poop, and urine (often times all at once). Instead of tracing lines on the screen to direct different types of aircraft towards a landing strip to prevent an accident, you'll be directing people into urinals and stalls to prevent "accidents" of a different kind.
If patrons run into each other, there will be blood spilled. If someone doesn't get to a stall on time, there will be urine on the floor. And oh yes -- there will be poop. The concept really isn't that hard to grasp.