While quite a bit more straightforward than the recent "Creative Kills" trailer, this video highlights stealth gameplay, a major element of Dishonored.
You'll be able to visualize enemies' lines of sight and, unless I'm mistaken, even how far the noise you make by running travels through the environment. And, of course, leaning. Lots and lots of leaning.
Something tells me I won't be pulling off any no-kill runs with this game; the end of the trailer looked all too familiar. Even still, all of the powers at my disposal certainly won't hurt.