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Mario, recreated out of glowing bacteria photo

Yes, that is Nintendo's iconic mascot, recreated in a petri dish out of magical glowing bacteria. This piece of biological retro nonsense was created by researchers from the University of Osaka, who genetically manipulated the bacteria to radiate fluorescent proteins and carotenoid pigments, which are science words that I don't want to understand. 

Science we may not know, but we do know silly gimmicky videogame references, and that's certainly what this is. Yes, these scientists could be curing cancer instead of doing this, but if I had to choose between a world free of disease or a world free of glowing bacteria Marios, I'm afraid all those little bald kids are on their own.

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Jim Sterling serves as reviews editor for Destructoid.com, head of the Podtoid podcast, and produces a number of news stories, original features, one-of-a-kind videos. With his passionate argumentative style, controversial opinions, harsh delivery, and dedication to brutal honesty Sterling is a name that you can't help but recognize. Likes PS2, iPod Touch, Silent Hill 2, Metal Gear Solid, Dynasty Warriors 3 Meet the rest of the team



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79 comments | showing # 1 to 50
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next 50 comments

Neonie's Avatar - Comment posted on 12/19/2009 08:04
Neonie
"I'm afraid all those little bald kids are on their own."

I lol'd and will await all the idiots who will soon take you way to seriously.
volatilis's Avatar - Comment posted on 12/19/2009 08:05
volatilis
Shame they can't cure your obesity.
Psychomax's Avatar - Comment posted on 12/19/2009 08:08
Psychomax
If I had cancer and saw this, I would still chuckle. And cough.
Jim Sterling's Avatar - Comment posted on 12/19/2009 08:11
Jim Sterling
Volatilis: Actually, medical science COULD make me not-fat, moron. Shame they can't cure your stupidity.
Jon B's Avatar - Comment posted on 12/19/2009 08:16
Jon B
SCIENCE!

This is awesome. I bet the people who are funding them shat a brick when they saw what all their money was turned into.
Super Drybones's Avatar - Comment posted on 12/19/2009 08:26
Super Drybones
Jim that's offensive, it should read

these scientists could be curing cancer instead of doing this, but if I had to choose between a world free of disease or a world "FULL" of glowing bacteria Marios

Now if only they could bring it to life and make it stomp things.
oxfordsquare's Avatar - Comment posted on 12/19/2009 08:28
oxfordsquare
Damn you Japan, you take all my bitterness and resentment for keeping FF XIII from us, only to bring me right back with this splendid demonstration of perfect uselessness.
Xzyliac's Avatar - Comment posted on 12/19/2009 08:49
Xzyliac
The future is a GO!
PreacherMan89's Avatar - Comment posted on 12/19/2009 09:00
PreacherMan89
Haha, that is awesome.
alexeternal's Avatar - Comment posted on 12/19/2009 09:13
alexeternal
@Jim: Untrue again, Brain synapses could be artificially stimulated to artificially create intelligence in the human brain. The percentage of death would be astronomical, but its SCIENCE.
Jim Sterling's Avatar - Comment posted on 12/19/2009 09:15
Jim Sterling
alexeternal: I think he should take that risk, definitely.
Xzyliac's Avatar - Comment posted on 12/19/2009 09:17
Xzyliac
Jim, at the risk of sounding like a stereotypical gamer, I think you just go owned with a bloody venegance.

Even if apparently the experiment would kill you.
The Juda's Avatar - Comment posted on 12/19/2009 09:28
The Juda
keep pushing it, jim. Enjoy it.
Naim Master's Avatar - Comment posted on 12/19/2009 09:43
Naim Master
@alexeternal
But then we really gotta ask ourselves, if we manipulated his brains, is he still volatilis or is he somenthing else?
volatilis's Avatar - Comment posted on 12/19/2009 09:45
volatilis
@Jim hit a nerve did I? You fat fucking hypocrite. It's ok to make fun of sick children but not so funny when we make fun of the fat man?

Keep sucking on those twinkies colossus.

Also, can you please point me in the direction of the 'cure' for obesity? Other than locking you in a box of course.
Kraid's Avatar - Comment posted on 12/19/2009 09:45
Kraid
This is hilarious , the comments I mean.
alexeternal's Avatar - Comment posted on 12/19/2009 09:53
alexeternal
@naim- the recpetors for logic and consciousness are in 2 seperate lobes of the brain, so theoretically he would be the same

@Jim- Can't say I disagree with you on that.
Super Drybones's Avatar - Comment posted on 12/19/2009 09:54
Super Drybones
Guys if it wasn't for fat and stupid people we wouldn't have the internet. Can't we all get along and make fun of Casual Gamers???
rottenvenetic's Avatar - Comment posted on 12/19/2009 09:56
rottenvenetic
This, I like. It's not as cool as the penguin army, but close enough.

Btw, these bacteria are not wholly useless, nor do they appear to be designed just to draw Mario the Elder with. Stuff that glows (or reacts in a visible but harmless way) like this can be useful in endoscopy and such practices if they are cued to react only to certain thresholds of temperature, presence of X substance etc.
Jim Sterling's Avatar - Comment posted on 12/19/2009 09:58
Jim Sterling
volatilis: No you didn't hit a nerve, moron. After three years of little kids like you, I think I'm more than used to the same old tired insults. I was merely making a joke, which seems have flown over your retarded head. The cures I jokingly refer to are, of course, stomach stapling and liposuction, which would cure of me of my terrible disease.

Unfortunately, your only option is that life-threatening brain synapse stimulation. Still, keep reaching for that rainbow. Maybe one day science will develop a safe cure for people with your affliction.
Not Gabe Newell's Avatar - Comment posted on 12/19/2009 10:00
Not Gabe Newell
Oh god this is amazingly funny.
Birdman the Friendly's Avatar - Comment posted on 12/19/2009 10:05
Birdman the Friendly
I honestly can't tell whether the people who make "HURR JIM IS FAT" jokes are serious or trolls anymore.
Kaspar's Avatar - Comment posted on 12/19/2009 10:10
Kaspar
Why so angry?
timtheterrible's Avatar - Comment posted on 12/19/2009 10:13
timtheterrible
I want this.
reindall's Avatar - Comment posted on 12/19/2009 10:33
reindall
There's nothing wrong with being fat. If Jim was an African tribeswoman, all the neighbouring villages' chiefs would battle over him and offer immense amounts of poultry and other goods for his hand.
bobyoko's Avatar - Comment posted on 12/19/2009 10:41
bobyoko
how is this a gimmick? seems more like a science project

@volatillis
HA HA HA HA HA
KrazyKraut's Avatar - Comment posted on 12/19/2009 10:56
KrazyKraut
ohhhhhh damn...jim ask niero if you can kick him..plz...guys like him sucks ass
lewness's Avatar - Comment posted on 12/19/2009 10:58
lewness
Uh, this story is PETA-proof, right? Because... the bacteria... err... *silence*
Everyday Legend's Avatar - Comment posted on 12/19/2009 11:02
Everyday Legend
@ volatilis
I kinda have to side with Jim on this one. You couldn't read the quite obvious sarcasm laced throughout the statement that "Yes, these scientists could be curing cancer instead of doing this..."

So, that would mean that you couldn't figure out that the point of his joke was that they not only could, but should be finding the cure for cancer so that people wouldn't have to suffer as they do. It only makes his defense sound much more plausible, as while he may be the resident fat guy, you look like the resident dipshit that couldn't take the time to read S L O W L Y.
Everyday Legend's Avatar - Comment posted on 12/19/2009 11:03
Everyday Legend
Also, +1 to sardonic British wit.
TheDreadHawk's Avatar - Comment posted on 12/19/2009 11:05
TheDreadHawk
SCIENCE!

Also, trolls.
DinnertimeNinja's Avatar - Comment posted on 12/19/2009 11:09
DinnertimeNinja
Well, once again, Volatilis delves increasingly deeper into the realm of stupidity.

It seems like he practically lives his life to make fun of ole' Jim now. Even when the post gives him no meaning to.

Truly, he is a Tard among men.
Ikey Heyman's Avatar - Comment posted on 12/19/2009 11:40
Ikey Heyman
c'mon guys, it's just for fun. I'm sure they're curing cancer in the meantime.

and this is awesome.
TickTock's Avatar - Comment posted on 12/19/2009 11:47
TickTock
Yay trolls! @Volatilis: You so crazay! As in you should be sectioned.

Here's some science; getting bacteria to express proteins is actually pretty useful. Although the fiddly bits are different, if you can shoehorn glowing jellyfish protein into the little guys, you can use it for all sorts of poop. This is probably only a few hours work to actually get the Mario up and growing anyway.
fetusmilk's Avatar - Comment posted on 12/19/2009 11:49
fetusmilk
cancer, prepare to me stomped.
volatilis's Avatar - Comment posted on 12/19/2009 11:49
volatilis
Ha ha ha the irony in this thread? Do any of you idiots sticking up for him stop to think that maybe there are quite a few young children undertaking chemo or some other life saving treatment that might find their belittlement a tad upsetting. Especially on a website geared towards children. How many bald sick children do you think play video games? Probably a lot. I guess the sickos amongst you find it funny. I don't and even more so at this time of year. So therefore I will layeth the smack down.

If Jim wants to make fun of them, then he best be prepared to take it also. If he can't take it, my advice is, don't write it. I am happy to listen to all rage at me for telling the truth. So feel free.

@JIM btw those are treatments you mention Jim NOT CURES. You can't CURE a fat person as FATNESS is not a disease. In the future, perhaps, with gene therapy, but NOTHING exists right now to cure it. FACT. Who's a moron now?
Jim Sterling's Avatar - Comment posted on 12/19/2009 12:00
Jim Sterling
"@JIM btw those are treatments you mention Jim NOT CURES. You can't CURE a fat person as FATNESS is not a disease. In the future, perhaps, with gene therapy, but NOTHING exists right now to cure it. FACT. Who's a moron now?"

I see you still haven't nailed the principle premise of a joke yet. Don't worry, you'll get it. Keep trying!
volatilis's Avatar - Comment posted on 12/19/2009 12:05
volatilis
@JIM I'm sorry did your argument just collapse?
Xhumation's Avatar - Comment posted on 12/19/2009 12:07
Xhumation
Those are some cool retro gaming bacteria.
volatilis's Avatar - Comment posted on 12/19/2009 12:09
volatilis
@JIM regarding your 'principles' concerning jokes, answer me this is it right or wrong to make fun of dying children?
Thane Vickers's Avatar - Comment posted on 12/19/2009 12:12
Thane Vickers
@volatilis
..geared for kids.. Ha ha ha HA!
volatilis's Avatar - Comment posted on 12/19/2009 12:18
volatilis
@robotic - I love how you take three words out of that paragraph and think it actually proves anything. how about you debate the whole thing?
volatilis's Avatar - Comment posted on 12/19/2009 12:19
volatilis
@JIM still no response Jim? Is it funny to make fun of dying children, yes or no?
Everyday Legend's Avatar - Comment posted on 12/19/2009 12:22
Everyday Legend
He wasn't making fun of sick children. He was making fun of how the efforts to make a glowing Mario could have been spent to cure them, you stupid fucking twat. I'd tell you to grow a brain, but you'll need ears and eyes to learn anything for its sake, so if you ever look a look at yourself you'd know that you look like an asshole that can't (or most likely won't) listen.

By the way, Destructoid ain't geared towards children. Well, maybe except for you.
volatilis's Avatar - Comment posted on 12/19/2009 12:26
volatilis
@ EverdayLegend @ he used the kids as his punchline. What humour class did you take my angry little friend? I don't have to point out how retarded you are, as it is plain to see for all with an actual brain and a grasp of the argument.

Yawn.
TickTock's Avatar - Comment posted on 12/19/2009 12:27
TickTock
@Volatilis: Jim was using sarcasmirony in a stab at humor at which point you decided to get your serious face on. It's not his fault you missed the joke. Made me laugh, but then perhaps I'm a sicko?
Jim Sterling's Avatar - Comment posted on 12/19/2009 12:28
Jim Sterling
"@JIM still no response Jim? Is it funny to make fun of dying children, yes or no?"

Sorry, unlike you I'm not hitting refresh every thirty seconds so I can't instantly respond to your inane drivel.

It's okay to make jokes about anything. There's a difference between a joke and a sincere attempt to hurt or upset somebody on a personal level. You seem unable to tell the difference. Luckily, smart people actually can.
volatilis's Avatar - Comment posted on 12/19/2009 12:30
volatilis
@TickTock, commendable that you admit to it! I like you, someone who recognises he did use them as a joke and is not afraid to admit he found it funny.

I did not miss the joke, just thought it was inappropriate.
CelicaCrazed's Avatar - Comment posted on 12/19/2009 12:30
CelicaCrazed
But this type of biotechnology has the potential to lead to fluorescent genetic markers to more accurately identify cancerous cells and to tell whether it is migrating or not. At the very least, it can help scientists to better understand the progression of cellular development and chemical pathways. There are so many processes that occur that we have no clue how they work but fluorescent markers actually allow us to visibly see what exactly is going on!

So yeah, it actually IS helping to cure cancer....indirectly of course :P
volatilis's Avatar - Comment posted on 12/19/2009 12:31
volatilis
@JIM Thank-you.
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