Usually I hate people who pull the ridiculous "play a real guitar" argument, but this advertisement for Sparrow's range of guitars is pretty classy. The general message is that no videogame can replace a real guitar, and I don't think anybody would argue that.
It's just that some of us think it's way more fun to play with plastic buttons.
Nevertheless, this is at least the coolest anti-Guitar Hero argument I've ever seen. Better than some hypocritical rock star whose music is in the games he's slagging off, at any rate.