That said, I'm no MMO guy.
Looking at the screenshot the buttons look bigger and seem to be on a flat surface, Naga buttons are on a convex surface, so it may be more comfortable.
my mouse the Sharkoon fireglider black has a lenght of 13cm/5.1 inch so its not the only one at that lenght.
Its an awesome budget mouse btw, still 3600dpi, good build quality, no bs on it, and two sets of spare skates for when they are damaged which has as of 2 years of use not really happened. the fireglider is also wider than the deathadder which makes it more comfortable if you use it with 3 fingers ( forefinger on the left mouse button, middle finger on the middle mouse button (scroll wheel) ring finger on the right mouse button)
I hope it has a normal scroll wheel and not the wonky crap that was on the G500. It was so loose I couldn't really use it for gaming, had them replace it with a G400.
Though I would set it to a keyboard shortcut.
Looking at it's shape, maybe the picture isn't giving it justice - but it looks uncomfortable compared to the naga.
Honestly, to me, it depends on the size of the mouse itself and your hand size.. I have small hands for a guy (proportional though, cause I'm not a big guy, either) and more often then not when I use a mouse with side buttons I can get my thumbs to most of them, cause they're usually too big if they have more then 2 extra buttons.
Also, yeah, what Excel said, this is pretty cheap compared to other mice with the same amount of buttons.. It'll probably be pretty solid too, I haven't personally ever had a bad logitech mouse in my lifetime.

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