I have some misgivings about Lego Star Wars III: The Clone Wars. For one, I think the lego mini figures look ridiculous with those big bulbous eyes. Second, I couldn't care less about The Clone Wars story. I enjoy the show, but it's usually just as good with the sound off.
The good news is, it looks like not all of the game will take place during The Clone Wars time-frame. According to a mini-interview with USAToday, we'll get to relive key scenes from the films as well, including a reenactment of the climactic battle at Geonosis at the end of Attack of the Clones. It might be tough to pull of a battle of that scope, but it sounds like Traveler's Tales up to the task. They're planning on pushing the game's engine as hard as they can, with +300 interactive characters planned for some scenes.
There will also be playable characters from other Star Wars storylines, such as The Force Unleashed, with over 175 playable characters in all. I seriously hope they stick an E.T. in there. Lego E.T. would kick ass.