If a recent ad posting on Gamasutra is to be believed, Silicon Knights is looking for fresh talent to work on a game, and that game may very well be Too Human 2. So far, all the world's babies have not cried out in tandem, so until that happens, the sequel has most definitely not been confirmed.
SK is looking for someone with experience in a range of game systems, "including combat, UI, inventory, progression, levels, NPC actions, play balance and reward schemes." They will also need to possess "familiarity with the fantasy and science fiction genre and role-playing games."
I can feel the bile rising in my throat as I type this, dreading the thought of yet more Too Human in the world. I hear the original design documents have been sealed in a twelve-foot-thick case made of alternating concrete and lead layers, before being shot into space.
Lord only knows of the wrath that Too Human 2 would wreak upon the world.