"Clint who?" you might ask? Well, this Clint! He scored all of Aronofsky's movies from Pi to Black Swan and yes, that includes the overused Requiem for a Dream melody that was found in practically every trailer with dramatic slow-motion action scenes -- until Inception's BRRRRM stole the crown for most overused film music cliché.
In an interview with The Quietus, Clint Mansell casually mentions that he is working on scoring Mass Effect 3. To Mansell, scoring a game is more like being a DJ who combines elements organically than it is with movies:
“You’ve got the holding pattern, then the big explosion where you need the score to kick in. Then you need to take it off on a tangent. You’ve got all these different elements that change depending on what the player does. You have to figure out an overall symphony, but be able to break it down into component parts. You can bring the pain when required."
It's often said that film music is at its best when it's experienced, just enough out of reach to not be explicitly aware of it being there. Other than Requiem for a Dream's famous theme, this has always been the case in Aronofsky films, so we should be in for a very atmospheric treat. Having said that, I'm sure we all want an epic orgy of recognizable Mass Effect themes in the ending cutscenes for Mass Effect 3.
While the full interview doesn't say anything else about the game, it's worth a read if you have a passing interest in the movies he scored or music in general.
Unspoilt By Progress: A Conversation With Clint Mansell [The Quietus via Eurogamer]