Invincible:
This brightly colored universe would totally lend itself to a action video game. Basically, Invincible has the powers of Superman, so it would totally lend itself to a cel-shaded sandbox superhero game.

Walking Dead:
Think a more serious version of Dead Rising with squad mechanics and more linear gameplay.

Marvel Zombies:
Play as your favorite zombie and battle your way to the end of life in the galaxy.

Y: The Last Man:
Keep your identity secret as you try to collect all the materials to help save humanity from extinction. Also, tons of sex mini-games.

Gantz:
This manga was created to be a video game. Crazy epic enemies, a obvious increase in monster difficulty and weapons, and a crazy-ass story line and characters to keep things interesting. As far as I know, no game has been made yet, but I think an american developer should pick this up and make it before some Japanese developer makes a shitty FPS out of it.

So, I have recently begun to hate my roommates solely for the fact that they refuse to play any games other than Marvel vs. Capcom 2 on Dreamcast. In my efforts to convince them that there are OTHER games out there, I brought up all the games they should play, giving me a total sense of nostalgia. I used to be seriously obsessed about fighting games on the Dreamcast, and Soul Calibur and MvC2 were like my gateway drugs. I tried to convince them to switch to Mark of the Wolves, Jojo's Bizarre Adventure, Plasma Sword, Third Strike (SF3), or Last Blade, but they will have none of it. This got me to thinking, why have fighting games fallen so far out of favor for modern gamers? Is it because they have become too competitive and tournament-obsessed?