I have to start this mini-review with the fact that I have a severe god-complex, and this game is my drug of choice. Prototype is an interesting beast, it's part hack n' slash, part GTA, part RPG, and I love it. There are, however, a few faults among the awesome that I'll point out below:

Graphics: 8/10
The graphics have been done much better, in higher profile titles. Graphics whores need not apply. Looks are somewhere between Saints Row 2 and GTA IV.

Animation: 8/10
Radical went a little light on fluidity of motion for Alex, but I've been surprised at the little slick parkour embellishes when I'm skyrocketing between buildings. It looks good, feels, good, but not as complete as it should be. Some questionable sneaking animations when impersonating a soldier, no one seems to notice the one guy who walks around like Solid Snake with a hunchback.

User Interface: 8/10
Very well put together, but the menus aren't infinitely scrolling, i.e you get to get end of the Upgrades menu and it doesn't cycle back to the beginning, it just stops.There's no way to set waypoints between areas, so it's kind of easy to get lost at first, but you'll start recognizing landmarks before long.

Presentation: 9/10
The game is fantastically presented; you will feel your power and flexibility of action grow organically as you unravel the mysteries behind your powers.

Voice Acting: 5/10
Some really bad compression issues with Alex's voice in cut-scenes, The actress playing Dana Mercer could use a few acting lessons.

Controls: 8/10
Alex is FAST. It's hard to get used to him moving around, because he is extremely responsive, which is great, but takes some finesse. Most of my complaints about the animation come from this. He moves really fast, and the momentum is not accurately figured into the equation sometimes. Alex feels flighty and weightless when you're trying to get him to haul his ass out of the way of a charging infected monster.

Music: ?/10
What music? I consume the minds and souls of the world. I am a god.
All kidding aside, the music is forgettable and really unobtrusive. I was so busy with killing that it didn't occur to me that there WAS a soundtrack.

Overall: 8/10 Above Average, Good Fun, Forgettable Audio
If you like annihilating a man by cutting him in half length-wise and then jumping 100 feet into the air to hijack a chopper, then give this a shot. Most of my complaints are technical, and have no bearing on the fun factor, which is a solid 10. The audio has some problems that are distracting from the story, but the radio/ped chatter in the open city is great.

A possible buy, definite rent.