How many versions of Dr. Mario has there been? There's the GB and NES versions, the SNES version, the N64 version, the GC version, the GBA version, the Classic NES version for GBA, the Dr.Wario version in WarioWare, the BrainAge 2 minigame.
Unless I missed something, this makes the 10th appearance of Dr. Mario. And has anything changed? No, not really. You are still killing of those bacteria like you have for 18 years.
The Wii version new features are online play via Nintendo-WiFi and the Bacteria Extermination mode, that is nothing more than the BrainAge 2 minigame.
The game works fine, but unless you are in for the online play or are a total Dr.Mario nut, there isn't much there for you.
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It's the same reason no one is begging for Chess 2 (at least I hope not).
Given enough time, someone will always try to reinvent the wheel.
Especially if they seem downright basic. Remember, pretty pictures + cute sound effects + few gameplay elements as possible = the gaming equivalent of premium crack cocaine (Zero Punctuation).
As far as puzzle games, they kind of stand for themselves. The repeats are usually just to have more platform exposure.
Its all more or less moot. Its just downsides of the genres.
I see. The virus are actually overdosing.